Adam Friedman

Compositions For Sustained Release Of Nitric Oxide, Methods Of Preparing Same And Uses Thereof

Application

#8333997 Dec 18, 2012

Filed

Jun 20, 2007

Inventor

Joel M. Friedman (South Orange, NJ) · Adam Friedman (New York, NY) · Mahantesh S. Navati (Bronx, NY)

Appl. No.

12/227657

Assignee

Albert Einstein College of Medicine of Yeshiva University (Bronx, NY)

International Classification

A61K 33/00, A61K 47/36, C01B 21/24, A01K 59/00, A01N 25/00

U.S. Classification

424718, 423405, 514788, 514929

Abstract

The invention provides compositions for releasing nitric oxide (NO) comprising a matrix that encapsulates nitric oxide. Nitric oxide is released when the composition is exposed to an aqueous...

Nanoparticle Delivery Vehicle For S-Nitroso-N-Acetyl Cysteine And Uses Thereof

Application

#2015014 May 28, 2015

Filed

May 1, 2013

Inventor

Adam J. Friedman (New York, NY) · Pedro Cabrales (San Diego, CA) · Joel M. Friedman (South Orange, NJ)

Appl. No.

14/399335

Assignee

Adam J. Friedman (New York, NY) · Pedro Cabrales (San Diego, CA) · Joel M. Friedman (South Orange, NJ)

International Classification

A61K 9/51, A61K 9/19, A61K 31/401, A61K 9/14, A61K 31/095, A61K 31/198

U.S. Classification

424489, 568 76, 514562, 514423, 514706

Abstract

Nanoparticles are provided that comprise S-nitrosothiol (SNO) groups covalently bonded to the nanoparticles and/or S-nitrosothiol containing molecules encapsulated within the nanoparticles, as well...

Systems And Methods For A Mixing Container

Application

#2016002 Feb 4, 2016

Filed

Jul 30, 2015

Inventor

Adam FRIEDMAN (Gainesville, VA) · Adam FRIEDMAN (Gainesville, VA)

Appl. No.

14/814448

Assignee

Adam FRIEDMAN (Gainesville, VA) · Adam FRIEDMAN (Gainesville, VA)

International Classification

A47J 43/27

Abstract

A disposable mixing system includes a lid having an opening and configured to hold contents within a container, a strainer configured to couple with the container and the lid in a position between...

Homoepitaxial Tunnel Barriers With Functionalized Graphene-On-Graphene And Methods Of Making

Application

#2017019 Jul 6, 2017

Filed

Mar 20, 2017

Inventor

Adam L. Friedman (Silver Spring, MD) · Olaf M. T. van 't Erve (Falls Church, VA) · Connie H. Li (Alexandria, VA) · Jeremy T. Robinson (Washington, DC) · Berend T. Jonker (Waldorf, MD)

Appl. No.

15/463229

Assignee

The Government of the United States of America, as represented by the Secretary of the Navy (Washington, DC)

International Classification

H01L 29/66, H01L 21/04, H01L 29/45, H01L 29/167, H01L 21/02, H01L 29/16

Abstract

This disclosure describes a method of making a tunnel barrier-based electronic device, in which the tunnel barrier and transport channel are made of the same material—graphene. A homoepitaxial tunnel...

Multistate Magnetic Memory Element Using Metamagnetic Materials

Application

#2019033 Oct 31, 2019

Filed

Apr 13, 2019

Inventor

Steven P. Bennett (Alexandria, VA) · Adam L. Friedman (Silver Spring, MD)

Appl. No.

16/383590

Assignee

The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, VA)

International Classification

G11C 11/16, H01L 43/10, H01L 43/08, H01L 43/12, G11C 11/56

Abstract

A metamagnetic tunneling-based spin valve device for multistate magnetic memory comprising an electronic memory logic element with four stable resistance states. A metamagnetic tunneling-based spin...

Cyclic Pentamer Compounds As Proprotein Convertase Subtilisin/Kexin Type 9 (Pcsk9) Inhibitors For The Treatment Of Metabolic Disorder

Application

#2023008 Mar 23, 2023

Filed

Nov 26, 2019

Inventor

Brian Addison DECHRISTOPHER (Belmont, MA) · Alec Nathanson FLYER (Cambridge, MA) · Adam FRIEDMAN (Cambridge, MA) · Christian GAMPE (Watertown, MA) · Andrei Alexandrovich GOLOSOV (Cambridge, MA) · Philipp GROSCHE (Riehenstrasse, DE) · Tyler HARRISON (Arlington, MA) · Qian LIU (Belmont, MA) · Justin Yik Ching MAO (North Reading, MA) · Lauren Gilchrist MONOVICH (Belmont, MA) · Tajesh Jayprakash PATEL (Westford, MA) · Carina Cristina SANCHEZ (Somerville, MA) · Liansheng SU (Winchester, MA) · Lihua YANG (Westford, MA) · Rui ZHENG (Lexington, MA)

Appl. No.

17/296895

Assignee

Brian Addison DECHRISTOPHER (Belmont, MA) · Alec Nathanson FLYER (Cambridge, MA) · Adam FRIEDMAN (Cambridge, MA) · Christian GAMPE (Watertown, MA) · Andrei Alexandrovich GOLOSOV (Cambridge, MA) · Philipp GROSCHE (Riehenstrasse, DE) · Tyler HARRISON (Arlington, MA) · Qian LIU (Belmont, MA) · Justin Yik Ching MAO (North Reading, MA) · Lauren Gilchrist MONOVICH (Belmont, MA) · Tajesh Jayprakash PATEL (Westford, MA) · Carina Cristina SANCHEZ (Somerville, MA) · Liansheng SU (Winchester, MA) · Lihua YANG (Westford, MA) · Rui ZHENG (Lexington, MA)

International Classification

C07K 7/56

Abstract

The disclosure relates to inhibitors of PCSK9 useful in the treatment of cholesterol lipid metabolism, and other diseases in which PCSK9 plays a role, having the Formula (I):