Maria Acosta

Compositions And Methods For Delivering Pharmaceutical Agents

Application

#2020033 Oct 29, 2020

Filed

Jan 18, 2019

Inventor

Stephen Black (Tucson, AZ) · Maria Acosta (Tucson, AZ)

Appl. No.

16/963043

Assignee

Stephen Black (Tucson, AZ) · Maria Acosta (Tucson, AZ)

International Classification

A61K 9/16, A61K 31/366, A61K 9/00, A61K 9/51

Abstract

Provided herein are compositions and methods for treating respiratory and pulmonary vascular disease. In particular, provided herein are spray dried simvastatin for delivery to the lung.

Eversible Branch Stent-Graft And Deployment Method

Application

#2009024 Oct 1, 2009

Filed

Mar 25, 2008

Inventor

Walter Bruszewski (Guerneville, CA) · Masoumeh Mafi (Santa Rosa, CA) · Shyam Nagasrinivasa (Santa Rosa, CA) · Maria D. Acosta De Acevedo (Rohnert Park, CA)

Appl. No.

12/055083

Assignee

Medtronic Vascular, Inc. (Santa Rosa, CA)

International Classification

A61F 2/06

U.S. Classification

623 116, 623 115, 623 135

Abstract

A method of deploying an eversible branch stent-graft includes deploying the eversible branch stent-graft into a main vessel such that a collateral opening in a main stent-graft of the eversible branch stent-graft is aligned with an ostium of a branch vessel emanating from the main vessel. A branch stent ring suture threaded though outer exposed crowns of an outer stent ring of the branch stent-graft is grasped and pulled through the collateral opening to evert the branch stent-graft into the branch vessel as a branch anchor suture is removed to release a protruding end of a branch stent-graft from a proximal end of the main stent-graft.

Compositions And Methods For Delivering Pharmaceutical Agents

Application

#2020030 Oct 1, 2020

Filed

Oct 25, 2018

Inventor

Rick G. Schnellmann (Tucson, AZ) · Maria F. Acosta (Tucson, AZ)

Appl. No.

16/759054

Assignee

Rick G. Schnellmann (Tucson, AZ) · Maria F. Acosta (Tucson, AZ)

International Classification

A61K 9/16, A61K 31/185

Abstract

Provided herein are compositions and methods for wound healing. In particular, provided herein are spray dried suramin for use in wound healing and other applications.

Compositions And Methods Of Detecting And Treating Thrombosis And Vascular Plaques

Application

#2022030 Sep 29, 2022

Filed

Jun 1, 2020

Inventor

Emmanuelle Joelle Meuillet (Tucson, AZ) · Iman Daryaei (Tucson, AZ) · Maria Fernanda Acosta (Tucson, AZ)

Appl. No.

17/616166

Assignee

Emmanuelle Joelle Meuillet (Tucson, AZ) · Iman Daryaei (Tucson, AZ) · Maria Fernanda Acosta (Tucson, AZ)

International Classification

A61K 49/22, A61K 41/00, A61K 47/51, A61K 47/26, A61P 7/02, A61K 47/10

Abstract

The invention provides nanodroplets labeled with targeting ligands that are useful in the detection and treatment of vascular thromboses (e.g., fibrin clots) and vascular plaques, or related diseases and conditions, as well as methods of preparation and use thereof.

Pin And Sleeve Devices

Application

#2021016 Jun 3, 2021

Filed

Jul 22, 2019

Inventor

Amit Pai (Farmingville, NY) · Maria Acosta (Bayside, NY) · Robert Cannetti (Lindenhurst, NY)

Appl. No.

16/481944

Assignee

LEVITON MANUFACTURING CO., INC. (Melville, NY)

International Classification

H01R 13/52, H01R 13/18, H01R 13/59

Abstract

An electrical pin and sleeve device is disclosed. The pin and sleeve device incorporating one or more features to provide improved protection (e.g., sealing) from the environment (e.g., rain, water, dust, etc.). Additionally, and/or alternatively, the pin and sleeve device may include one or more features to facilitate easier assembly and use. For example, the outer housing of the pin and sleeve device may include an inwardly extending projection defining a shelf for contacting a grommet positioned within the outer housing of the pin and sleeve device. Additionally, and/or alternatively, the pin and sleeve devices may incorporate a cable boot to provide an improved seal between the electrical cable and the clamp nut to prevent the ingress of water, dust, or the like.

Alkylated Nucleosides, And Compositions And Methods Thereof For Nucleic Acid Delivery

Application

#2023004 Feb 9, 2023

Filed

Jan 7, 2021

Inventor

Emmanuelle Joelle Meuillet (Tucson, AZ) · Maria F. Acosta (Tucson, AZ) · Dillon Hanrahan (Tucson, AZ)

Appl. No.

17/790697

Assignee

Emmanuelle Joelle Meuillet (Tucson, AZ) · Maria F. Acosta (Tucson, AZ) · Dillon Hanrahan (Tucson, AZ)

International Classification

A61K 9/107, A61K 47/68, A61K 47/54, C12N 15/11

Abstract

The invention provides novel compounds, compositions and formulations of liposomes, microbubbles and/or nanodroplets, and emulsions thereof, that are useful in delivery of various nucleic acids and genes (e.g., single stranded RNA, DNA, si-RNA and CRISPR constructs), as well as methods of preparation and use thereof including methods of imaging and gene delivery using ultrasound activation.