Michelle Long

Crystalline Form Of The Compound A-348441

Application

#8124129 Feb 28, 2012

Filed

Jul 12, 2006

Inventor

Russell Drew Cink (Grayslake, IL) · Daozhong Zou (Bridgewater, NJ) · Marvin Robert Leanna (Grayslake, IL) · Pascal H. Toma (Cary, NC) · Michelle Andrée Long (Libertyville, IL)

Appl. No.

11/988330

Assignee

Karo Bio AB (Huddinge)

International Classification

A61K 9/14, A61K 31/56

U.S. Classification

424489, 514179, 514177, 514178

Abstract

There is provided a hemihydrate of (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17β-hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11β-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2θ=6. 580. 2, 8. 54+0. 2, 12. 280. 2, and 19. 680. 2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.

Water-In-Oil-In-Water Compositions

Application

#5942216 Aug 24, 1999

Filed

Feb 21, 1997

Inventor

Craig A. Herb (Chicago, IL) · Liang Bin Chen (Lombard, IL) · Judy B. Chung (Glenview, IL) · Michelle A. Long (Lombard, IL) · Wei Mei Sun (Palatine, IL)

Appl. No.

8/804365

Assignee

Helene Curtis, Inc. (Chicago, IL)

International Classification

A61K 713, A61K 742, A61K 9113, B01J 1300

U.S. Classification

424 7028

Abstract

Water-in-oil-in-water multiple emulsion compositions are disclosed. The multiple emulsion compositions comprise an external aqueous phase optionally incorporating a surfactant system capable of forming liquid crystals as an emulsifier. The internal phase comprises a primary water-in-oil emulsion, wherein the primary emulsion comprises a first topically-active compound, a surfactant phase, an oil phase, and water.

Salts Of Fenofibric Acid And Pharmaceutical Formulations Thereof

Application

#2008005 Feb 28, 2008

Filed

Aug 17, 2007

Inventor

Russell Cink (Grayslake, IL) · Joseph Paterson (Vernon Hills, IL) · Yi Gao (Vernon Hills, IL) · Geoff Zhang (Libertyville, IL) · Michelle Long (Libertyville, IL) · John Morris (Grayslake, IL) · Joerg Rosenberg (Ellerstadt, DE)

Appl. No.

11/840477

Assignee

Russell Cink (Grayslake, IL) · Joseph Paterson (Vernon Hills, IL) · Yi Gao (Vernon Hills, IL) · Geoff Zhang (Libertyville, IL) · Michelle Long (Libertyville, IL) · John Morris (Grayslake, IL) · Joerg Rosenberg (Ellerstadt, DE)

International Classification

A61K 31/192, A61K 31/495, A61P 3/00, C07C 59/76, C07D 241/02

U.S. Classification

514252120, 514571000, 544358000, 562460000

Abstract

In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

Salts Of Fenofibric Acid And Pharmaceutical Formulations Thereof

Application

#7259186 Aug 21, 2007

Filed

Jun 30, 2004

Inventor

Russell Drew Cink (Grayslake, IL) · Yi Gao (Vernon Hills, IL) · Geoff G. Z. Zhang (Libertyville, IL) · Michelle A. Long (Libertyville, IL) · John B. Morris (Grayslake, IL) · Joerg Rosenberg (Ellerstadt, DE)

Appl. No.

10/880851

Assignee

Abbott Laboratories (Abbott Park, IL)

International Classification

A61K 31/19, A61K 31/495, C07C 59/76, C07D 241/02

U.S. Classification

514571, 51425212, 562460, 544358

Abstract

In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients. In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.

Rinse-Off Water-In-Oil-In-Water Compositions

Application

#6022547 Feb 8, 2000

Filed

Jun 28, 1996

Inventor

Craig A. Herb (Chicago, IL) · Liang Bin Chen (Lombard, IL) · Judy Chung (Glenview, IL) · Michelle A. Long (Lombard, IL) · Wei Mei Sun (Palatine, IL) · Gerald P. Newell (Hoffman Estates, IL) · Trefor A. Evans (Lombard, IL) · Kimberly Kamis (Glenview, IL) · Richard M. Brucks (Chicago, IL)

Appl. No.

8/670853

Assignee

Helene Curtis, Inc. (Chicago, IL)

International Classification

A61K 700

U.S. Classification

424401

Abstract

Rinse-off, water-in-oil-in-water multiple emulsion compositions are disclosed. The multiple emulsion compositions comprise an external aqueous phase optionally incorporating an emulsifier and/or a second topically-active compound. The internal phase comprises a primary water-in-oil emulsion, wherein the primary emulsion comprises a first topically-active compound, a surfactant phase, an oil phase, and water.

Salts Of Fenofibric Acid And Pharmaceutical Formulations Thereof

Application

#2009026 Oct 22, 2009

Filed

Jun 23, 2009

Inventor

Russell D. Cink (Grayslake, IL) · Joseph B. Paterson (Vernon Hills, IL) · Yi Gao (Vernon Hills, IL) · Geoff G. Z. Zhang (Libertyville, IL) · Michelle A. Long (Libertyville, IL) · John B. Morris (Grayslake, IL) · Joerg Rosenberg (Ellerstadt, DE)

Appl. No.

12/490174

Assignee

ABBOTT LABORATORIES (Abbott Park, IL) · FOURNIER LABORATORIES IRELAND LTD (COUNTY CORK)

International Classification

A61K 9/48, A61K 31/366, A61K 9/00, A61P 9/00

U.S. Classification

424452, 514460, 424400

Abstract

In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at least one enteric binder, and optionally iii) other physiologically acceptable excipients.In a second aspect, the present invention relates to novel salts of fenofibric acid that are photostable when compared to other salts of fenofibric acid.